Of the 9 thrift stores listed in Picayune, 8 give a phone number, 1 publishes opening hours and 5 have a website. 3 are branches of national chains — Goodwill (3); the remaining 6 are independent. By what they offer: 4 accept donations, 2 sell online, 1 has a furniture section. The nearest bigger selection is Gulfport with 23.
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HOPE Thrift by Pearl River County SPCA
245 Frontage Rd, Picayune, MS 39466-7587
Tue-Fri 9:30am-5:30pm, Sat 10am-4pm
Sells furniture, books, toys, art & decor, vintage
Holds regular sales — ask the store about current deals
Donations: during business hours · takes resalable items · not accepted: clothing or shoes
Where proceeds go: caring for and rehoming pets in need
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Goodwill Picayune Retail Store and Donation Center
795 Memorial Blvd, Picayune, MS 39466
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Jacob's Well Ministries
600 Highway 11 S, Picayune, MS 39466-5308
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Goodwill
795 Memorial Blvd, Picayune, MS 39466
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Picayune Goodwill
901 Palestine Rd, Picayune, MS 39466-4317
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Twice as Nice
120 Street A, Picayune, MS 39466-3021
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Merly's Trading Post
3343 MS-43, Picayune, MS 39466
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Storms'PoppinTags
2105 E Canal St, Picayune, MS 39466-4808
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Picayune Rags To Riches Thrift Store
320 S Curran Ave, Picayune, MS 39466-5322
Before you go
Store details marked on the cards come from each store's own website, checked August 2026.
By feature
Mississippi: rank 13 · Our methodology